Novel ketone body therapy for managing Alzheimer's disease: An Editorial Highlight for Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic …

MA Puchowicz, TN Seyfried - Journal of Neurochemistry, 2017 - Wiley Online Library
MA Puchowicz, TN Seyfried
Journal of Neurochemistry, 2017Wiley Online Library
… A treatment strategy that involves a ketone ester diet is novel and has promise as an
alternate therapy to the current clinical regimes for the management of AD. In the
highlighted paper, ‘Effects of a dietary ketone ester on hippocampal glycolytic and TCA
cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease’,
Pawlosky and colleagues provide compelling evidence showing that a dietary ketone ester
can target multiple pathologies seen in 3xTgAD mouse model of AD (Pawlosky et al. 2017; …
Read the highlighted article ‘Effects of a dietary ketone ester on hippocampal glycolytic and tricarboxylic acid cycle intermediates and amino acids in a 3xTgAD mouse model of Alzheimer's disease’ on page 195.
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